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Wanting to create child survival and healthy family programs Project Hope initially began working in Kyrgyzstan in 2002. Leading a group of international NGOs implementing the Healthy Family Program, a large-scale maternal, child, and reproductive health initiative, across three of the largest and most populous countries in Central Asia, Project HOPE was able to broker a national and regional policy in support of the plan.

HOPE's mission later grew to include the region-wide tuberculosis program in 2004, with the goal of helping improve the effectiveness of the local health system in response to Tuberculosis (TB) and in 2007, a new health of women and children program including a breastfeeding promotion and a family planning/reproductive health initiative. The family planning/reproductive health component taught the standard day method, a natural form of birth control, using CycleBeads™. The program included distribution of 10,000 sets of CycleBeads and the eventual development of local production of the beads for a sustainable supply.

Currently, HOPE is conducting a five year USAID funded partnership with Population Services International (PSI) to increase access to TB prevention and treatment among at-risk populations in Uzbekistan, Tajikistan, Kazakhstan and Kyrgyzstan. The initiative provides direct outreach services and training to those populations most at-risk and focuses on increasing TB and HIV knowledge and prevention as well as training for providers on stigma reduction.

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Participants in the 2015 training session for TB in Tajikistan The First Regional TB Infection Prevention and Control Training at the National TB IC Training Center in Tajikistan
With the success of the project, the idea of using the National Training Center as a regional training base for CAR was supported by the NTP managers of Uzbekistan, Kyrgyzstan and Kazakhstan.

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